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Acute-19 is the only turbine ventilator of its characteristics that has been developed and validated in Spain in an animal model during the confinement period decreed on 14 March. There are several teams in Spain, both from companies as well as research centers, that have developed models of bag mask ventilators, or mechanical manual balloons, or with a compressed gas compressor, in order to send oxygen into the patient. But the operation of turbine ventilators, such as Acute-19, is better in terms of the stability of gas flow than those that work with other motor systems. Unlike other ventilators being developed, Acute-19 is based on a turbine that has a set of sensors and actuators to accurately regulate the air output pressure that is sent to the patient, making it possible to adjust inspiratory and expiratory pressure parameters, respiratory frequency and inspiration-expiration relation.
In addition to these differential features, there is now the fact that very few devices have thus far surpassed the animal model testing of their prototypes.
For these reasons, with this validation at the CEU UCH we have taken a very important step forward for the Acute-19 model to start being manufactured in order to ease the current need for suitable ventilators for Covid-19 patients." Professor José Ignacio Redondo Next clinical phase
The Acute-19 project team now starts the clinical phase with a prior observational study in patients with no respiratory pathology, at the Hospital Universitario La Fe of Valencia, headed by anaesthesiologist José Miguel Alonso, project director, with the collaboration of specialists Guido Mazzinari, Óscar Díaz, Jorge Puchol and María Pilar Argente. Alonso also stresses the ease of the design and efficiency of ventilators based on turbines, the components of which can be obtained easily: "These are important advantages regarding its manufacturing and development, which is why we hope to begin their manufacturing soon and make them available to anyone who needs to produce them anywhere in the world by way of an open source system on the project website, http://acute19.com/."
This design of the Acute-19 prototype, which has now been tested, has been developed by a multidisciplinary team comprised by José Ramírez Paz, from the Universidad de Córdoba; Damià Rizo Morant, from Darimo Carbon S.L.; Pedro Alonso Pérez, from Tecnikoa 3d Filaments S.L.; and José Miguel Alons Íñigo, head of the VMNI CR Group of Experts in Non-Invasive Therapies of Valencia. Source:
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