High-fiber diet can reverse adverse effects of environmental toxins on cardiovascular health

High-fiber diet can reverse adverse effects of environmental toxins on cardiovascular health

Research from the University of Kentucky's Superfund Research Center (UK-SRC) shows that a diet high in fiber could possibly reverse the adverse effects that environmental toxins have on cardiovascular health. The findings are part of UK-SRC's "Project #1," which examines how nutrients affect toxicity caused by polychlorinated biphenyls (PCBs) in vascular tissues. PCBs are man-made chemicals that were used in industrial and commercial applications and have been linked to a number of adverse health effects in humans and animals. Although they were banned more than 40 years ago, PCBs can still be released into the environment from poorly maintained hazardous waste sites. Prior UK-SRC research in the lab of Bernhard Hennig, a professor in UK's Department of Animal & Food Sciences, found a connection between PCBs and cardiovascular disease. Pan Deng, a postdoctoral researcher working in Hennig's lab, is continuing this research with a study that found that nutrients including fiber reduced PCB toxicity in multiple organ systems, including gut microbiota, liver and vasculature. Using animal models, we found that eating a high-fiber diet can prevent pollutant-induced cardiovascular disease. This finding may lead to nutritional and therapeutic interventions in people who are exposed to PCBs." Pan Deng, a postdoctoral researcher Related Stories



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