MDPI Publishing

MDPI Publishing

Recent technological developments provide easy access to use an artificial oxygen supply (hyperoxia) during exercise training. The aim of this study was to assess the efficacy of a commercially available oxygen compressor inducing low-dose hyperoxia, on limiting factors of endurance performance. Thirteen active men (age 24 ± 3 years) performed a high-intensity interval exercise (HIIE) session (5 × 3 min at 80% of W max , separated by 2 min at 40% W max ) on a cycle ergometer, both in hyperoxia (4 L∙min −1 , 94% O 2 , HYP) or ambient conditions (21% O 2 , NORM) in randomized order. The primary outcome was defined as red blood cell deformability (RBC-D), while our secondary interest included changes in muscle oxygenation. RBC-D was expressed by the ratio of shear stress at half-maximal deformation (SS 1 / 2 ) and maximal deformability (EI max ) and muscle oxygenation of the rectus femoris muscle was assessed by near-infrared spectroscopy. No statistically significant changes occurred in SS 1 / 2 and EI max in either condition. The ratio of SS 1 / 2 to EI max statistically decreased in NORM ( p < 0.01; Δ: −0.10; 95%CI: −0.22, 0.02) but not HYP ( p > 0.05; Δ: −0.16; 95%CI: −0.23, −0.08). Muscle oxygenation remained unchanged. This study showed that low-dose hyperoxia during HIIE using a commercially available device with a flow rate of only 4 L·min −1 may not be sufficient to induce acute ergogenic effects compared to normoxic conditions. Keywords: oxygen therapy; oxygen supplementation; FiO 2 ; oxygen kinetics; hemorheologic response; NIRS; interval exercise oxygen therapy ; oxygen supplementation ; FiO 2 ; oxygen kinetics ; hemorheologic response ; NIRS ; interval exercise This MDPI and ACS Style Freitag, N.; Böttrich, T.; Weber, P.D.; Manferdelli, G.; Bizjak, D.A.; Grau, M.; Sanders, T.C.; Bloch, W.; Schumann, M. Acute Low-Dose Hyperoxia during a Single Bout of High-Intensity Interval Exercise Does Not Affect Red Blood Cell Deformability and Muscle Oxygenation in Trained Men—A Randomized Crossover Study. Sports 2020 , 8 , 4. AMA Style Freitag N, Böttrich T, Weber PD, Manferdelli G, Bizjak DA, Grau M, Sanders TC, Bloch W, Schumann M. Acute Low-Dose Hyperoxia during a Single Bout of High-Intensity Interval Exercise Does Not Affect Red Blood Cell Deformability and Muscle Oxygenation in Trained Men—A Randomized Crossover Study. Sports . 2020; 8(1):4. Freitag, Nils; Böttrich, Tim; Weber, Pia D.; Manferdelli, Giorgio; Bizjak, Daniel A.; Grau, Marijke; Sanders, Tanja C.; Bloch, Wilhelm; Schumann, Moritz. 2020. "Acute Low-Dose Hyperoxia during a Single Bout of High-Intensity Interval Exercise Does Not Affect Red Blood Cell Deformability and Muscle Oxygenation in Trained Men—A Randomized Crossover Study." Sports 8, no. 1: 4. Find Other Styles Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here . Article Metrics