Research could aid in development of antiperspirants, treatment of sweat gland disorders

Research could aid in development of antiperspirants, treatment of sweat gland disorders

Research looks at best ways to disinfect N95 masks for reuse Cultured cells are useful for elucidating the function of human eccrine sweat gland myoepithelial cells; however, up until now, no human eccrine sweat gland cell line has retained the characteristics of myoepithelial cells. In 2016, the research team established a method enabling human eccrine sweat gland cells to maintain the characteristics of myoepithelial cells for a short time by culturing human eccrine sweat gland myoepithelial cells under conditions similar to those in vivo . We focused on the fact that human eccrine sweat gland myoepithelial cells cultured in an environment similar to that in vivo form a spherical structure covered with myoepithelial cells. Direct introduction of an immortalizing gene into the spherical structure enabled us to efficiently immortalize human eccrine sweat gland myoepithelial cells, achieving a breakthrough in generating iEM cells." Fumihiro Okada, study lead Human eccrine sweat gland myoepithelial cells could previously be subcultured for only around three generations. iEM cells, on the other hand, can be subcultured for more than ten generations. Moreover, iEM cells express α-smooth muscle actin (α-SMA), a gene that supports the function of human myoepithelial cells, retaining their properties (Fig.2). Now, the material transfer agreement for iEM cells allows the cells to be transferred through Applied Biological Material Inc. to research institutes in many countries worldwide. "We expect that iEM cells, as a new test system for sweat glands, will aid in the development of antiperspirants, treatment of sweat gland disorders, and regeneration of sweat gland tissue." Source:



Also in Industry News

How to decide whether or not to start treatment for prostate cancer?
How to decide whether or not to start treatment for prostate cancer?

0 Comments

How to decide whether or not to start treatment for prostate cancer?

Read More

Analysis of the SARS-CoV-2 proteome via visual tools
Analysis of the SARS-CoV-2 proteome via visual tools

0 Comments

Analysis of the SARS-CoV-2 proteome via visual tools

Read More

$65m investment increases British Patient Capital’s exposure to life sciences and health technology
$65m investment increases British Patient Capital’s exposure to life sciences and health technology

0 Comments

$65m investment increases British Patient Capital’s exposure to life sciences and health technology

Read More