Researchers use new eye movement test to study brain aging effects

Researchers use new eye movement test to study brain aging effects

Researchers analyze the aftereffects of deferred intentions in the brain Researchers from the University's Department of Eye and Vision Science, led by Dr Paul Knox, developed a new test, using measurements of eye movements, to provide an improved method of investigating inhibitory control, and have applied to study the effects of aging on this ability. Study In the study two cohorts of healthy people were recruited from two different age groups, 19 to 27 years old and 50 to 72 years old. Participants viewed a dot in the center of a computer a screen and then had to to look at a second dot that appeared to the left or right not when it appeared, but when it disappeared. As people instinctively look at things when they appear, this requires the inhibition of a normal automatic eye movement. Eye movements were measured precisely using an infrared eye tracker, revealing how often they looked too early. Results The results showed that older participants were much more likely to look at the dot when it appeared (not when it diapered) and were slower compared to younger participants. Dr Paul Knox, said: We are designed to react to things appearing in our visual world. It is something we do automatically. However, we also have the ability to stop ourselves responding and this prevents us becoming slaves to our sensory environment. This new test allows us to measure inhibitory behavior precisely. It is clear that older participants found it more difficult to inhibit their actions, even once we had accounted for the general slowing that occurs with aging. This confirms that a decline in inhibitory control is a part of normal aging. We are doing experiments to refine the test, and then we hope to use it to study inhibitory control in a range of important diseases." Source: University of Liverpool Journal reference: Knox​, P.C & Pasunuru, N . (2020) Age-related alterations in inhibitory control investigated using the minimally delayed oculomotor response task. PeerJ . doi.org/10.7717/peerj.8401 .



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