Weight loss surgery helps reverse respiratory issues in obese patients
The most common symptoms reported by the patients include fever, cough, and fatigue. Less common symptoms include headache, coughing up blood, sputum production, and diarrhea. Half of the patients developed shortness of breath or difficulty breathing.
About 82 patients presented with fever, 81 of them had a cough, and a third of the patients experienced the difficulty of breathing and shortness of breath. Five patients, who were critically ill, developed coinfections with fungi and bacteria.
Most of the patients also developed lymphopenia, a condition of having abnormally low levels of lymphocytes, which are important for immune response. Lymphopenia is linked to an ongoing infection and immunodeficiency, or the immune system doesn’t have the ability to fight serious infections.
Most of the patients manifested pneumonia with abnormal findings on chest CT scan, while the common complications seen in the patients include acute respiratory distress syndrome (ARDS), acute cardiac injury, and secondary infection. Of the patients, 17 developed ARDS and 11 of them succumbed to multiple organ failure.
Treatment included antivirals, antibiotics, and oxygen therapy. Among the patients, about half are still admitted to the hospital and a third has been discharged as of Jan. 25.
“The 2019-nCoV infection caused clusters of severe respiratory illness similar to severe acute respiratory syndrome coronavirus and was associated with ICU admission and high mortality. Major gaps in our knowledge of the origin, epidemiology, duration of human transmission, and clinical spectrum of the disease need fulfillment by future studies,” the authors concluded and recommended in the study.
Though the study involved a large number of patients, more data is needed to determine accurate data about the disease process, manifestations, and health outcomes of those infected with the deadly virus. Journal reference:
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Huang, Chaolin et al. The Lancet, https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30183-5/fulltext
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