The U.S. can erase cervical cancer in two decades

The U.S. can erase cervical cancer in two decades

Researchers discover new approach to make tumors sensitive to immunotherapy Screening can detect precancerous changes in the cervix, which, if not treated, can lead to cancer. The CDC encourages boys and girls to get vaccinated against HPV between the ages of 11 and 12. Women are also encouraged to have a screening test called a PAP smear every three years when they reach the ages of 21 to 29 years old. It will take two decades The study is the first one to estimate a timeframe for eliminating cervical cancer in the U.S. To land to their findings, the team used two disease modeling platforms to compare nine various HPV vaccination and cervical cancer screening treatments. The model, which was adapted for Japan, helped the team evaluate the expected number of cervical cancer cases and deaths over the lifetime of participants who were born between 1994 and 2007. From there, they evaluated the possibility for each scenario to achieve a threshold for the elimination of four cases per 100,000 women and then one case per 100,000 women. The team found that cervical cancer elimination can be achieved by 2038 to 2046, increasing screening coverage to 90 percent in 2020 was the best way to speed up the elimination of the disease. This means that 1,400 to 2,088 cases will not occur each year between 2019 and 2100. At present, about 14 percent of women are never screened. On the contrary, reaching 90 percent HPV vaccine coverage in adults between 26 and 45 years old was found to have little effect on the cases of cervical cancer. “Across all three analyses, we were able to project the vast number of cervical cancer cases and deaths averted globally by ensuring high uptake of both prevention and treatment services for cervical cancer," Megan Smith, program manager at the Cancer Council New South Wales in Australia and co-author said. "Together with the WHO elimination initiative, we hope this analysis will galvanize public health efforts to improve access to both primary and secondary cervical cancer prevention in the U.S.," Jane Kim, professor of health decision science at Harvard Chan School and senior author, added. Sources: World Health Organization (WHO). (2020). Cervical Cancer. https://www.who.int/cancer/prevention/diagnosis-screening/cervical-cancer/en/ U.S. Centers for Disease Control and Prevention (CDC). (2020). Basic Information About Cervical Cancer. https://www.cdc.gov/cancer/cervical/basic_info/ Journal reference: Simms, K., Hanley, S., Smith, M., Keane, A., Canfell, K, et al. (2020). Impact of HPV vaccine hesitancy on cervical cancer in Japan: a modelling study. The Lancet Public Health. https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(20)30010-4/fulltext



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