Industry News
Neural Stem Cell Transplantation May Improve Cognitive Function in Brain Cancer - The ASCO Post
The potentially devastating long-term consequences on cognitive function in patients with brain cancer following cranial irradiation led Charles L. Limoli, PhD, Professor of Radiation Oncology, University of California, Irvine, to study neural stem cell transplantation and how the procedure may prevent cognitive decline in this setting. Although an effective treatment for brain cancers, radiation therapy can sometimes induce debilitating side effects, including disruptions in memory and concentr...
Hirschsprung's Disease Genetic Analysis Reveals Mix of Common, Rare Risk Variants
NEW YORK (GenomeWeb) – Genetic factors that contribute to a highly heritable developmental condition called Hirschsprung's disease include a complex suite of risk variants, ranging from common polymorphisms in non-coding elements to rarer coding variants and copy number variants (CNVs), according to new research from investigators at Johns Hopkins University, the University of Washington, the Broad Institute, and New York University.
"In our study, we found that the risk of the complex phenotype...
Correction to: Modulation of lipolysis and glycolysis pathways in cancer stem cells changed multipotentiality and differentiation capacity toward endothelial lineage
In the publication of this article [1], there is an error in one of the contributing author names.
The error: ‘Jalal Abdolali Zade’
Should instead read: ‘Jalal Abdolalizadeh’
Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, prov...
Protein Expression: basic concepts to new directions
Date: Tuesday, 11 June, 2019
Time: 09:30 – 13:00
Place: Fèlix Serratosa, Parc Cientific de Barcelona (PCB)
This short workshop will describe many aspects of heterologous expression in E.coli, from choice of construct design through to methods to improve the levels of soluble expression and options for co-expression. In addition, it will also address expression in eukaryotic hosts, including secreted proteins and ECDs, and options for co-expression.
The workshop will finish with a discussion an...
Gene Transfer Therapy Is Producing Prolonged Remissions in Patients with Advanced Leukemia - The ASCO Post
In August 2011, researchers from the University of Pennsylvania published their breakthrough findings of a pilot study showing sustained remissions of up to 1 year in a small number of patients with advanced chronic lymphocytic leukemia (CLL) who had been treated with genetically engineered versions of their own T cells. The study results, published in both The New England Journal of Medicine1 and Science Translational Medicine,2 were the first to show prolonged responses using gene transfer the...
Study of Supercapacitive activity of Eu-MOF as an electrode material - New Journal of Chemistry (RSC Publishing)
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High surface area and redox activity are indispensable characteristics for a material to be considered as an electrode material in pseudocapacitors. In this regard, redox active metals-based metal-organic frameworks (MOFs) with high surface area, can function...
Chromosome-level de novo assembly of the pig-tailed macaque genome using linked-read sequencing and HiC proximity scaffolding
Old world monkey species share over 93% genome homology with humans and develop many disease phenotypes similar to those of humans, making them highly valuable animal models for the study of numerous human diseases. However, the quality of genome assembly and annotation for old world monkeys including macaque species lags behind the human genome effort. To close this gap and enhance functional genomics approaches, we employed a combination of de novo linked-read assembly and scaffolding using pr...
Tanshinone IIA induces apoptosis in fibroblast-like synoviocytes in rheumatoid arthritis via blockade of the cell cycle in the G2/M phase and a mitochondrial pathway.
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Mitochondria- and Oxidative Stress-Targeting Substances in Cognitive Decline-Related Disorders: From Molecular Mechanisms to Clinical Evidence
Copyright © 2019 Imane Lejri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Alzheimer’s disease (AD) is the most common form of dementia affecting people mainly in their sixth decade of life and at a higher age. It is an extensively studied neurodegenerative disorder yet incurable to date. While its main postmortem brain ha...
List of all elements found in ribosomes?
Hello,
I am trying to find a breakdown of all the elements that a ribosome complex would contain.
Any feedback appreciated!
This could be estimated from knowing the composition of the ribosome (how long are the ribosomal RNAs and ribosomal proteins) and the average elemental composition of nucelic acids and proteins.
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